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     Residency Program
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       Eric Sribnick, M.D.
E-mail:


Hometown:
Charleston, SC

Medical School:
Medical University of South Carolina

Undergraduate:
Presbyterian College (Clinton, SC)

Area of interest:
General Neurosurgery, Translational Research

Hobbies:
Spending time with my family, Film, Literature, Anything Outdoors

Awards:
Distinguished Honor Graduate, College of Graduate Studies, MUSC, 2007
Neurosurgery Student Award, Department of Neurosurgery, MUSC, 2007
Marian Kies Memorial Award, American Society for Neurochemistry, 2006

Publications:
Reviews and Book Chapters:
Sribnick EA, Goldblatt MR, Campbell JW, Roberts JR. Moyamoya disease in a four-month-old: a case study. *Clinical Pediatrics*. 2003, 42:281-284.

Sribnick EA, Wingrave JM, Matzelle DD, Ray SK, Banik NL. Estrogen as a neuroprotective agent in the treatment of spinal cord injury. *Annals of the **New York** **Academy** of Science*. 2003, 993:125-33.

Sribnick EA, Ray SK, Banik NL. Estrogen as a multi-active neuroprotective agent in traumatic injuries. *Neurochemical Research*. 2004, 29:2007-2014.

Guyton MK, Sribnick EA, Ray SK, Banik NL. A role for calpain in optic neuritis. *Annals of the **New York** **Academy** of Sciences*. 2005, 1053:48-54.

Guyton MK, Sribnick EA, Wingrave JM, Ray SK, Banik NL. Axonal Damage and Neuron Death in MS and EAE: A Pivotal Role for Calpain in Demyelination. In: Waxman S, ed. Multiple Sclerosis as a Neuronal Disease. New York: Academic Press. 2005, pp 293-304.

Ray SK, Guyton MK, Sribnick EA, Banik NL. Calpain as a Target for Prevention of Neuronal Death in Injuries and Diseases of the Central Nervous System. In: Lathja A and Banik NL, 3rd ed. Handbook of Neurochemistry and Molecular Neurobiology: Neural Protein Metabolism and Function, Volume 7. New York: Springer Publisher. 2006, pp 445-467.

Sribnick EA, Guyton MK, Imam SA, Ray SK, Banik NL. Calpain's role as a central mediator in diverse neurodegenerative processes. In: Festschrift in Honor of Harry B. Bradford. Westbury: PJD Publications, 2007, pp 3-24.

Research Manuscripts:
Sur P, Sribnick EA, Wingrave JM, Nowak MW, Ray SK, Banik NL. Estrogen attenuates oxidative stress-induced apoptosis in C6 glial cells. *Brain Research*. 2003, 971:178-188.

Ray SK, Matzelle DD, Sribnick EA, Guyton MK, Wingrave JM, Banik NL. Calpain inhibitor prevented apoptosis and maintained transcription of proteolipid protein and myelin basic protein genes in rat spinal cord injury. *Journal of Chemical Neuroanatomy*. 2003, 26:119-124.

Wingrave JM, Schaecher KE, Sribnick EA, Wilford GG, Ray SK, Hazen-Martin DJ, Hogan EL, Banik NL. Early induction of secondary injury factors causing activation of calpain and mitochondria-mediated neuronal apoptosis following spinal cord injury in rats. *Journal of Neuroscience Research*. 2003, 73:95-104.

Sribnick EA, Ray SK, Nowak MW, Li L, Banik NL. 17b-estradiol attenuates glutamate-induced apoptosis and preserves electrophysiologic function in primary cortical neurons. *Journal of Neuroscience Research*. 2004, 76:688-696.

Wingrave JM, Sribnick EA, Wilford GG, Matzelle DD, Mou JA, Ray SK, Hogan EL, Banik NL. Relatively low levels of calpain expression in juvenile rat correlate with less neuronal apoptosis after spinal cord injury. *Experimental Neurology*. 2004, 187:529-532.

Wingrave JM, Sribnick EA, Wilford GG, Matzelle DD, Mou JA, Ray SK, Hogan EL, Banik NL. Higher calpastatin levels correlate with resistance to calpain-mediated proteolysis and neuronal apoptosis in juvenile rats after spinal cord injury. *Journal of Neurotrauma*. 2004, 21:1240-1254.

Chera B, Schaecher KE, Rocchini A, Imam SZ, Sribnick EA, Ray SK, Ali SF, Banik NL. Immunofluorescent labeling of increased calpain expression and neuronal death in the spinal cord of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice. *Brain Research*. 2004, 1006:150-156.

Sur P, Sribnick EA, Patel SJ, Ray SK, Banik NL. Dexamethasone decreases temozolomide-induced apoptosis in human glioblastoma T98G cells. *Glia*. 2005, 50:160-167.

Das A, Sribnick EA, Wingrave JM, Wilford GG, Delre AM, Woodward JJ, Appel SH, Banik NL, Ray SK. Calpain activation in apoptosis of ventral spinal cord 4.1 (VSC4.1) motoneurons exposed to glutamate: calpain inhibition provides functional neuroprotection. *Journal of Neuroscience Research*. 2005, 81:551-562.

Guyton MK, Wingrave JM, Wilford GG, Sribnick EA, Matzelle DD, Ray SK, Banik NL. Upregulation of calpain correlates with increased neuronal cell death and axonal degeneration in the spinal cord of Lewis rats with experimental allergic encephalomyelitis. *Journal of Neuroscience Research*. 2005, 81:53-61.

Sribnick EA, Wingrave JM, Matzelle DD, Wilford GG, Ray SK, Banik NL. Estrogen attenuated markers of inflammation and decreased lesion volume in acute spinal cord injury in rats. *Journal of Neuroscience Research*. 2005, 82:283-293.

Sribnick EA, Ray SK, Banik NL. Estrogen prevents glutamate-induced apoptosis in C6 glioma cells by a receptor-mediated mechanism. *Neuroscience*. 2005, 137: 197-209.

**Sribnick EA, Matzelle DD, Ray SK, Banik NL. Estrogen treatment of spinal cord injury attenuates calpain activation and apoptosis. *Journal of Neuroscience Research*, 2006, 84: 1064-1075.



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